Chris Zou

Hey, I'm Chris. I'm a PhD student at Stanford Genetics. I am interested in computer systems that enable us to model and engineer the physical world, especially biology.

Previously, I worked at FutureHouse on agents for science, at Datavant on medical record retrieval, and founded Health Engine. At Berkeley, I studied Computer Science and Biochemistry and was involved in the Accel Scholars program.

If you would like to collaborate or if there's any way I can help you, please reach out at cwzou [at] stanford [dot] edu.

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Updates

Research

Multiplexed epigenetic memory editing using CRISPRoff sensitizes glioblastoma to chemotherapy
Katie Lin, Christopher Zou, Akane Hubbard, Sasha Sengelmann, Laine Goudy, I-Ching Wang, Rohit Sharma, Joanna Pak, Kyla Foster, Tomoko Ozawa, John F de Groot, Joanna Phillips, Harish N Vasudevan, David R Raleigh, Alexander Marson, Niren Murthy, Luke A Gilbert, Mitchel S Berger, S John Liu
Neuro-Oncology, 2025

We show that transient delivery of a site-specific epigenetic memory editor can induce stable, complete, and multiplexed suppression of target genes for therapeutic application in GBM.

In vivo perturb-seq of cancer and microenvironment cells dissects oncologic drivers and radiotherapy responses in glioblastoma
S. John Liu, Christopher Zou, Joanna Pak, Alexandra Morse, Dillon Pang, Timothy Casey-Clyde, Ashir A. Borah, David Wu, Kyounghee Seo, Thomas O'Loughlin, Daniel A. Lim, Tomoko Ozawa, Mitchel S. Berger, Roarke A. Kamber, William A. Weiss, David R. Raleigh, Luke A. Gilbert
Genome Biology, 2024

We developed the first in vivo perturb-seq platform in intact tumors, providing a target discovery and data generation tool.

Fun stuff

Bookshelf

Breackneck, Dan Wang
Abundance, Ezra Klein, Derek Thompson
The Power Broker, Robert Caro
An Immense World, Ed Yong
Material World, James Conway
more...